The Efficacy of Fibrin Glue in Surgical Treatment of Conjunctivochalasis With Epiphora.

Nam, Kiyup; Jo, Young Joon; Lee, Sung Bok

doi:2010.51.4.498

J Korean Ophthalmol Soc > Volume 51(4); 2010 > Article

Original Article

Journal of the Korean Ophthalmological Society 2010;51(4):498-503.
DOI: https://doi.org/10.3341/jkos.2010.51.4.498 Published online April 15, 2010.

The Efficacy of Fibrin Glue in Surgical Treatment of Conjunctivochalasis With Epiphora.

Kiyup Nam, Young Joon Jo, Sung Bok Lee

¹Department of Ophthalmology, Chungnam National University College of medicine, Daejeon, Korea. sblee@cnu.ac.kr
²Research Institute for Medical Science, Chungnam National University, Daejeon, Korea.

눈물 흘림을 호소하는 결막이완증 환자의 수술적 치료에서 파이브린 글루의 유용성

남기엽¹ㆍ조영준^1,2ㆍ이성복^1,2

Department of Ophthalmology, Chungnam National University College of medicine¹, Daejeon, Korea Research Institute for Medical Science, Chungnam National University², Daejeon, Korea

Abstract

PURPOSE
To investigate the efficacy of fibrin glue used in conjunctival resection for conjunctivochalasis with epiphora. METHODS: Twenty-three patients (42 eyes) with conjunctivochalasis without nasolacrimal duct obstruction underwent conjunctival resection using either absorbable sutures (11 patients, 20 eyes, Group 1) or fibrin glue (12 patients, 22 eyes, Group 2) to attach the conjunctiva to the sclera. Outcomes recorded were improvement of epiphora, postoperative discomfort, and operation time. Postoperative discomfort was analyzed only in one eye (right eye) in case that the both eyes were operated. RESULTS: Epiphora completely improved in 6 eyes (30%) in Group 1 and 8 eyes (36.4%) in Group 2, partially improved in 9 eyes (45%) and 8 eyes (36.4%), and did not improved in 5 eyes (25%) and 6 eyes (27.2%), respectively (p=1.000). On the first day postoperatively, postoperative eye discomfort developedin 7 eyes (63.6%) in Group 1 and 5 eyes (41.7%) in Group 2 (p=0.414). Throughout the following week, the discomfort lasted in 6 eyes (54.5%) in Group 1 and 1 eye (13.6%) in Group 2 (p=0.027). The mean operation time was 25.0 (+/-2.6) minutes in Group 1 and 12.0 (+/-2.4) minutes in Group 2 (p<0.001). CONCLUSIONS: The success rates were similar in the two groups. However, the use of fibrin glue significantly reduces the postoperative discomfort and the operation time. Therefore, the use of fibrin glue in conjunctival resection of conjunctivochalasis seems to be an effective method.

Key Words: Conjunctivochalasis;Conjunctival resection;Fibrin glue