Osteogenic Sarcoma following Irradiation for Retinoblastoma.

Kim, Jae Myung; Youn, Dong Ho; Paik, Buk Won; Kim, Yong Il; Ham, Eui Keun

Original Article

Journal of the Korean Ophthalmological Society 1967;8(3):37-41.

Osteogenic Sarcoma following Irradiation for Retinoblastoma.

Jae Myung Kim, Dong Ho Youn, Buk Won Paik, Yong Il Kim, Eui Keun Ham

¹Department of Ophthalmology, School of Medicine, Seoul National Univertity, Seoul, Korea.
²Department of Ophthalmology, Seoul Red Cross Hospital, Seoul, Korea.
³Department of Pathology, School of Medicine, Seoul National University, Seoul, Korea.

방사선 (放射線) 조사에 (照射) 수반된 (隋伴) 안와골원성육종 (眼窩骨原性肉腫)

윤동호(Dong Ho Yoon),김재명(Jae Myung Kim),백북원(Book Won Baek),김영일(Young Il Kim),함의근(Eui Keun Ham)

Abstract

A case of Osteogenic sarcoma arised from orbit 4 years after the radiation therapy for retinoblastoma in a 9 years old girl is presented. 4 Years ago, under the diagnosis of retinoblastoma, the left orbital exenteration was performed and was treated with x-ray radiation giving 4.500 gamma tumor dose in 4, weeks. On admission, the left orbital cavity was filled with hard mass and orbital bone revealed extensive destruction with osteoplastic changes on x-ray, and diffuse sarcomatous growth of anaplastic cells with abundant osteogenesis and osteoclastic activity microscopically. It is of authors' opinion that osteogenic sarcoma of orbital bone in this presented case might developed by irradition on retinoblastoma.