| Serum Concentration of Lycopene in Normal and Glaucoma Patients. |
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Hae Yun Chung, Seung Hyuck Lee, Yang Cha Lee, Young Jae Hong |
1Department of Food and Nutrition, Yonsei University The Graduate School, Korea.
2Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. yjhong0815@yumc.yonsei.ac.kr
3Department of Ophthalmology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Korea. |
| 정상인과 녹내장 환자의 혈청 라이코펜 농도 |
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정혜연 ( Hae Yun Chung ) , 이승혁 ( Seung Hyuck Lee ) , 이양자 ( Yang Cha Lee ) , 홍영재 ( Young Jae Hong ) |
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| Abstract |
PURPOSE
We measured serum lycopene concentration and compared it in normal subjects, normal tension glaucoma (NTG), primary open angle glaucoma (POAG) patients. METHODS: We investigated serum lycopene concentration on 226 subjects, which were divided into 3 groups : group 1 with 136 normal subjects, group 2 with 24 NTG patients, group 3 with 66 POAG patients. Serum concentration of lycopene was measured by high performance liquid chromatography (HPLC). RESULTS: Mean age was 64.1+/-9.2 years old in group 1, 56.4+/-1.2 years old in group 2, 53.8+/-5.3 years old in group 3. Sex ratio (male:female) was 1:1 in group 1, 1.18:1 in group 2, 0.94:1 in group 3 respectively. Serum lycopene concentration was 6.44+/-0.34 microgram/dl in group 1, 2.55+/-0.44 microgram /dl in group 2, 2.17+/-0.27 microgram /dl in group 3 respectively. CONCLUSIONS: Serum lycopene concentration was significantly lower in NTG, POAG patients than normal subjects (P<.05). Further nutritional survey is necessary for new modality of treatment of glaucoma. |
| Key Words:
Lycopene;Normal tension glaucoma;Primary open angle glaucoma |
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