Evaluation of Chorioretinal Toxicity of Steroid after Intrachoroidal Injection in Rabbit. |
Hyung Woo Kwak, Jong Geun Shin, Jae Myung Kim |
Department of Ophthalmology, College of Medicine, Kyunghee University, Seoul, Korea. |
가토에서 후부맥락막내 스테로이드 주입후 맥락망막의 조직학적 소견 |
곽형우(Hyung Woo Kwak),김재명(Jae Myung Kim),신종근(Jong Geun Shin) |
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Abstract |
To determine the ocular toxicity after intrachoroidal steroid injection in the rabbit eye, 0.15ml(40 mg/ml) triamcinolone acetonide, 0.15ml(40 mg/ml) methylprednisol one acetate and 0.15ml balanced salt solution(as controls) were injected into the choroid. The results were shown normal in fundus examination, electroretinography, and electron microscopy throughout the two weeks course of the experiment. From these result, it would appear that intrachoroidal 6 mg steroid injection demonstrated the lack of ocular toxicity. |
Key Words:
Chorioretinal toxicity;Intrachoroidal needle insertion;Methylprednesolone;Pathology;Triamcinolone |
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