J Korean Ophthalmol Soc > Volume 62(1); 2021 > Article |
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Normal | early AMD | Intermediate AMD | Late AMD | p-value | |
---|---|---|---|---|---|
Total | 6,835 | 104 | 75 | 4 | |
Age (years)* | 49.5 ± 7.71 | 55.2 ± 8.38 | 60.4 ± 9.41 | 61.5 ± 11.09 | <0.001 |
Sex (male) | 4,507 (65.94) | 77 (74.04) | 44 (58.67) | 4 (100) | 0.076 |
Weight (kg)* | 68.21 ± 11.98 | 68.18 ± 12.40 | 64.10 ± 10.41 | 67.73 ± 10.29 | 0.407 |
Systolic BP (mmHg)* | 123.7 ± 14.98 | 123.6 ± 14.53 | 125.4 ± 15.56 | 124.0 ± 9.63 | 0.740 |
Diastolic BP (mmHg)* | 75.76 ± 10.74 | 76.25 ± 10.88 | 74.85 ± 10.68 | 83.00 ± 14.79 | 0.855 |
BMI* | 24.34 ± 3.20 | 24.42 ± 3.06 | 23.96 ± 2.59 | 23.17 ± 3.33 | 0.118 |
Drinking status† | 2,450 (35.84) | 48 (16.15) | 23 (30.67) | 2 (50.00) | 0.212 |
Exercise status† | 5,258 (76.93) | 78 (75.00) | 53 (70.67) | 3 (75.00) | 0.606 |
Current smoking† | 1,339 (19.59) | 24 (23.08) | 16 (21.33) | 1 (25.00) | 0.803 |
Hypertension† | 1,154 (16.88) | 29 (27.88) | 17 (22.67) | 3 (75.0) | <0.001 |
Diabetes† | 431 (6.31) | 10 (9.62) | 10 (13.33) | 0 | 0.043 |
hepatitis A Ab† | 5,757 (84.23) | 94 (90.38) | 74 (98.67) | 4 (100.0) | 0.002 |
hepatitis B Ab† | 5,335 (78.05) | 75 (72.12) | 57 (76.00) | 3 (75.0) | 0.515 |
hepatitis B Ag† | 192 (2.81) | 5 (4.81) | 5 (6.67) | 0 | 0.140 |
hepatitis C Ab† | 11 (0.16) | 0 | 0 | 0 | 0.961 |
Blood test | |||||
WBC* | 6.03 ± 1.63 | 6.25 ± 1.86 | 5.95 ± 1.52 | 6.57 ± 1.97 | 0.491 |
RBC* | 4.9 ± 0.45 | 4.9 ± 0.43 | 4.7 ± 0.43 | 4.9 ± 0.39 | 0.003 |
Hemoglobin* | 14.86 ± 1.58 | 15.14 ± 1.36 | 14.60 ± 1.45 | 15.60 ± 0.84 | 0.102 |
Platelet* | 260.1 ± 57.79 | 255.4 ± 50.21 | 262.3 ± 52.87 | 256.3 ± 32.79 | 0.855 |
Fasting glucose* | 95.1 ± 20.99 | 100.5 ± 27.83 | 97.6 ± 17.47 | 100.5 ± 21.63 | 0.044 |
AST* | 26.7 ± 15.41 | 27.5 ± 11.19 | 28.5 ± 13.54 | 38.8 ± 11.95 | 0.303 |
ALT* | 27.9 ± 20.91 | 28.0 ± 15.26 | 26.0 ± 15.60 | 35.8 ± 18.39 | 0.755 |
ALP* | 65.0 ± 18.94 | 68.3 ± 18.06 | 71.7 ± 17.67 | 73.5 ± 3.79 | 0.005 |
Total cholesterol* | 195.2 ± 35.53 | 194.7 ± 35.18 | 193.1 ± 39.91 | 185.0 ± 37.64 | 0.892 |
Triglyceride* | 135.2 ± 94.84 | 150.0 ± 189.12 | 131.4 ± 85.39 | 110.8 ± 28.37 | 0.424 |
HDL* | 56.6 ± 16.11 | 56.5 ± 16.10 | 57.3 ± 16.10 | 59.5 ± 17.29 | 0.969 |
LDL* | 132.0 ± 33.96 | 129.8 ± 34.80 | 128.9 ± 37.02 | 121.8 ± 40.89 | 0.712 |
ESR* | 14.0 ± 11.10 | 15.6 ± 12.46 | 19.8 ± 13.94 | 17.3 ± 10.21 | <0.001 |
GGT* | 42.1 ± 69.54 | 50.2 ± 52.60 | 39.4 ± 46.46 | 39.25 ± 8.50 | 0.675 |
CEA* | 2.0 ± 2.57 | 2.6 ± 1.80 | 2.8 ± 1.80 | 2.2 ± 0.46 | 0.016 |
CRP | 0.11 ± 0.31 | 0.15 ± 0.28 | 0.15 ± 0.26 | 0.08 ± 0.07 | 0.537 |
Values are presented as mean ± standard deviation or number (%).
AMD = age-related macular degeneration; BP = blood pressure; BMI = body mass index; Ab = antibody; Ag = antigen; WBC = white blood cell; RBC = red blood cell; AST = aspartate transaminase; ALT = alanine aminotransferase; ALP = alkaline phosphatase; HDL = high density lipoprotein; LDL = low density lipoprotein; ESR = erythrocyte sedation rate; GGT = gamma glutamyl transferase; CEA = carcinoembryonic antigen; CRP = C-reactive protein.
Normal | AMD | p-value | |
---|---|---|---|
Total | 549 | 183 | |
Age (years)* | 57.46 ± 9.18 | 57.45 ± 9.20 | 0.998 |
Sex (male) | 376 (68.49) | 125 (68.31) | 0.963 |
Weight (kg)* | 67.6 ± 11.13 | 66.5 ± 11.70 | 0.269 |
Systolic BP (mmHg)* | 126.8 ± 17.31 | 124.4 ± 14.94 | 0.085 |
Diastolic BP (mmHg)* | 76.6 ± 11.63 | 75.8 ± 10.89 | 0.431 |
BMI* | 24.5 ± 2.94 | 24.2 ± 2.88 | 0.224 |
Drinking status† | 162 (29.51) | 73 (39.89) | 0.009 |
Exercise status† | 469 (85.43) | 134 (73.22) | <0.001 |
Current smoking† | 62 (11.29) | 41 (22.40) | <0.001 |
Hypertension† | 184 (33.52) | 49 (26.78) | 0.090 |
Diabetes† | 55 (10.02) | 20 (10.93) | 0.725 |
hepatitis A Ab† | 521 (94.90) | 172 (93.99) | 0.635 |
hepatitis B Ab† | 425 (77.41) | 135 (73.77) | 0.314 |
hepatitis B Ag† | 10 (1.82) | 10 (5.46) | 0.009 |
hepatitis C Ab† | 3 (0.55) | 0 | 0.316 |
Blood test | |||
RBC* | 4.8 ± 0.43 | 4.8 ± 0.44 | 0.375 |
Hemoglobin* | 14.9 ± 1.27 | 14.9 ± 1.41 | 0.980 |
Platelet* | 248.7 ± 55.96 | 258.1 ± 50.90 | 0.043 |
Neutrophil* | 52.4 ± 9.04 | 52.4 ± 8.13 | 0.953 |
Lymphocyte* | 37.1 ± 8.32 | 37.3 ± 7.83 | 0.851 |
Monocyte* | 7.1 ± 1.96 | 7.0 ± 1.70 | 0.432 |
Eosinophil* | 2.8 ± 2.01 | 2.8 ± 2.56 | 0.871 |
Basophil* | 0.50 ± 0.31 | 0.51 ± 0.29 | 0.680 |
Fasting glucose* | 98.3 ± 18.97 | 99.3 ± 23.94 | 0.571 |
AST* | 26.5 ± 11.77 | 28.1 ± 12.27 | 0.103 |
ALT* | 27.0 ± 15.29 | 27.3 ± 15.45 | 0.771 |
ALP* | 66.1 ± 15.39 | 69.8 ± 17.74 | 0.007 |
Total cholesterol* | 188.7 ± 34.15 | 193.8 ± 37.06 | 0.085 |
Triglyceride* | 138.4 ± 90.04 | 141.5 ± 152.72 | 0.737 |
HDL* | 54.3 ± 14.83 | 56.9 ± 16.17 | 0.045 |
LDL* | 126.5 ± 31.72 | 129.3 ± 35.66 | 0.319 |
ESR* | 14.7 ± 11.07 | 17.3 ± 13.15 | 0.009 |
GGT* | 35.8 ± 32.11 | 45.6 ± 49.73 | 0.002 |
CEA* | 2.2 ± 1.39 | 2.6 ± 1.78 | <0.001 |
CRP* | 0.10 ± 0.14 | 0.15 ± 0.27 | 0.001 |
Values are presented as mean ± standard deviation or number (%).
AMD = age-related macular degeneration; BP = blood pressure; BMI = body mass index; Ab = antibody; Ag = antigen; RBC = red blood cell; AST = aspartate transaminase; ALT = alanine aminotransferase; ALP = alkaline phosphatase; HDL = high density lipoprotein; LDL = low density lipoprotein; ESR = erythrocyte sedation rate; GGT = gamma glutamyl transferase; CEA = carcinoembryonic antigen; CRP = C-reactive protein.
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