Diagnostic Criteria of Pattern VEP in Adult Monocular Amblyopic Patients.

Lim, Sun Hee; Lim, Key Hwan

doi:2013.54.12.1875

J Korean Ophthalmol Soc > Volume 54(12); 2013 > Article

Original Article

Journal of the Korean Ophthalmological Society 2013;54(12):1875-1881.
DOI: https://doi.org/10.3341/jkos.2013.54.12.1875 Published online December 13, 2013.

Diagnostic Criteria of Pattern VEP in Adult Monocular Amblyopic Patients.

Sun Hee Lim, Key Hwan Lim

Department of Ophthalmology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea. Limkh@ewha.ac.kr

성인 단안 약시 환자에서의 문양시유발전위 검사의 진단적 기준

임선희⋅임기환

Department of Ophthalmology, Ewha Womans University Mokdong Hospital, Ewha Womans University School of Medicine, Seoul, Korea

Abstract

PURPOSE
To suggest a diagnostic criteria of pattern visual evoked potential (VEP) in adult monocular amblyopic patients in comparison to normal subjects. METHODS: The medical records of patients' military service certificates from January 2000 to December 2011 were reviewed. The parameters of pattern VEP were analyzed by comparing monocular amblyopic patients with normal controls. RESULTS: This study included 47 monocular amblyopia and 39 normal control patients. All parameters of pattern VEP were statistically significantly different between monocular amblyopic eyes and normal eyes. The cut-off values for diagnosis of adult amblyopia using receiver operating characteristic (ROC) curve were 113.50 msec (P100 latency), 1.05 (ratio of P100 latency), 8.50 msec (interocular difference of P100 latency), and 5.25 microV (interocular difference of P100 amplitude). Cut-off value sensitivities were generally low: (51.1%, 70.2%, 53.2%, and 31.9%, respectively). CONCLUSIONS: The value of pattern VEP parameters had limitations due to low sensitivity and could be considered as ancillary diagnostic criteria when diagnosing amblyopia.

Key Words: Adult;Diagnostic criteria;Monocular amblyopia;Parameters of pattern VEP;ROC